Five Canadian warships left Halifax on Monday for a three-week training exercise with the U.S. navy, reports said.
The flagship of the exercise will be HMCS Montreal, which will be jointed by HMCS Ville de Quebec, Summerside, Moncton and Preserver, Navy officials said.
The vessels will join three U.S. destroyers, along with Canadian fighter jets and land forces.
Canada's only operational submarine, HMCS Windsor, is also expected to take part.
About 1,000 personnel will participate in the exercise, set to take place in waters off Canada's Nova Scotia and Norfolk of U.S. Virginia and Boston, Mass.
Joint Task Force Atlantic is one of several regional command centres responsible for conducting domestic operations under Canada Command. The centres were announced last year to focus on disasters at home.
Combat capabilities will be tested in the areas of anti-submarine warfare, electronic warfare and boarding operations.